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[Cardioembolic stroke: epidemiology]
1Unidad de Ictus, Servicio de Neurología, Hospital Universitario 12 de Octubre, Madrid, Spain. jdiaz.hdoc@salud.madrid.org
Insights
Cardioembolic stroke, often caused by atrial fibrillation, has a high mortality and recurrence rate. Early prevention and treatment are crucial due to its severity and greater disability compared to other strokes.
Area of Science:
- Cardiology
- Neurology
- Epidemiology
Context:
- Cardioembolic stroke accounts for approximately 25% of all ischemic strokes.
- Non-valvular atrial fibrillation is the primary cause, followed by myocardial infarction and other cardiac conditions.
- The incidence is estimated at 30 cases per 100,000 person-years, with higher prevalence in older adults.
Purpose:
- To highlight the significant impact of cardioembolic stroke.
- To underscore the high mortality and recurrence rates associated with this condition.
- To identify key risk factors contributing to cardioembolic events.
Summary:
- One in four ischemic strokes is cardioembolic, predominantly linked to non-valvular atrial fibrillation.
- This stroke type exhibits high hospital mortality, poor 5-year survival, and a greater recurrence risk (12% at 3 months) than non-cardioembolic strokes.
- Severity and resulting disability are substantial, with age, prior stroke, hypertension, diabetes, and heart failure as contributing factors.
Impact:
- Cardioembolic strokes lead to greater disability and higher mortality rates.
- The recurrence rate is significantly higher than non-cardioembolic strokes, emphasizing the need for effective prevention.
- Understanding risk factors is essential for developing targeted strategies to reduce stroke incidence and improve patient outcomes.
Abstract:
Approximately one in four ischemic strokes is of cardioembolic origin. Non-valvular atrial fibrillation accounts for 50% of these cases, followed by myocardial infarction, intraventricular thrombus, valvular heart disease and a miscellany of causes. The incidence of embolic heart disease in the population could be about 30 cases per 100,000 inhabitants per year, and its prevalence between 5 and 10 cases per 1,000 persons aged 65 years or older. Hospital mortality is high, and 5-year survival is only one out of every five patients. The recurrence rate of this type of stroke is about 12% at 3 months, higher than that of non-cardioembolic stroke. The severity of cardioembolic strokes and the resulting disability are greater than with non-cardioembolic stroke. Age, a history of stroke or transient ischemic attack, hypertension, diabetes and heart failure play a role in stroke with atrial fibrillation as additional risk factors for future embolisms. Stroke rates can reach over 20% per year and therefore the prevention and treatment of these events are of paramount importance.
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