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Related Experiment Video

Updated: May 21, 2026

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators
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Minimally invasive fetal therapy.

Tim van Mieghem1, David Baud, Roland Devlieger

  • 1Department of Obstetrics and Gynecology, Fetal Medicine Unit, University Hospitals Leuven, Leuven, Belgium.

Best Practice & Research. Clinical Obstetrics & Gynaecology
|June 12, 2012
PubMed
Summary

Prenatal therapy offers hope for fetal anomalies that worsen during pregnancy. Minimally invasive procedures can treat conditions like twin-to-twin transfusion syndrome, improving fetal and neonatal outcomes.

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Area of Science:

  • Perinatology
  • Fetal Medicine
  • Minimally Invasive Surgery

Background:

  • Advances in pregnancy screening and medical imaging enable earlier detection of fetal anomalies.
  • Some fetal conditions progress in utero, leading to severe morbidity or demise.
  • This necessitates exploring prenatal therapeutic interventions.

Purpose of the Study:

  • To provide an overview of minimally invasive prenatal therapies.
  • To discuss the rationale, technical aspects, and outcomes of these procedures.

Main Methods:

  • Review of common minimally invasive prenatal therapies.
  • Includes intrauterine transfusion, fetal cardiac procedures, interventions for urinary tract obstruction, thoracic pathology, fetoscopic laser for twin-to-twin transfusion syndrome, and selective reduction for complicated monochorionic twins.

Main Results:

  • Details on the rationale, techniques, and outcomes for various prenatal interventions are presented.
  • Specific conditions addressed include twin-to-twin transfusion syndrome and complex monochorionic twin pregnancies.

Conclusions:

  • Minimally invasive prenatal therapies are increasingly important for managing fetal conditions.
  • These interventions offer potential to improve fetal and neonatal outcomes for specific disorders.