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Gastrointestinal bleeding and blood transfusion in the elderly in Japan
Taketoshi Suehiro1, Yoichi Yakeishi, Fumitaka Sakai
1Department of Surgery, Shin-Nakama Hospital, Nakama, Japan. taketoshisuehiro2004@yahoo.co.jp
Insights
Elderly patients with gastrointestinal bleeding (GIB) often require more blood transfusions, especially if using antithrombotic drugs. This study suggests a restrictive transfusion strategy is feasible for managing GIB across age groups.
Area of Science:
- Gastroenterology
- Hematology
- Geriatrics
Background:
- Gastrointestinal bleeding (GIB) incidence rises with age.
- Blood transfusions are common for GIB management.
- Age-related differences in GIB and transfusion needs require investigation.
Purpose of the Study:
- To summarize data on patients with GIB.
- To analyze the relationship between blood transfusion and age in GIB patients.
- To compare transfusion management in elderly versus younger GIB patients.
Main Methods:
- Patients with GIB were categorized into two age groups: elderly (≥75 years) and younger (<75 years).
- Causes and clinical outcomes, including blood transfusions, were compared between groups.
- Analysis focused on transfusion requirements and pre-transfusion hemoglobin levels.
Main Results:
- Out of 120 GIB patients, 31% received blood transfusions.
- Elderly patients, particularly those on antithrombotic drugs, required greater transfusion volumes.
- Elderly patients without antithrombotics had significantly lower hemoglobin levels than younger counterparts.
Conclusions:
- The study's blood transfusion strategy appears compatible with a restrictive approach.
- Findings highlight age-related variations in transfusion needs for GIB.
- Further research may refine transfusion guidelines for elderly GIB patients.
Background/Aims:
The incidence of gastrointestinal bleeding (GIB) increases with age and blood transfusion is frequently given for the management of GIB. In this report, we summarized our data of the patients with GIB and discussed the relationship between blood transfusion and age in patients with GIB.
Methodology:
The patients were divided into two groups according to age, following elderly (≥75 years old) and younger (<75 years old) group. The causes and clinical outcome (blood transfusions, management) of each group were compared.
Results:
One-hundred and twenty patients with GIB were hospitalized (59 men, 61 women) with a mean age of 72.0±15.8 years (range 16-96 years old). Thirty-one patients (25.8%) received blood transfusion. The mean pre-transfusion hemoglobin was 6.4±1.2g/dL (elderly 6.3±1.4, younger 6.6±1.0g/dL) and the mean amount of blood transfusion was 2.8±1.6U (elderly 3.2±1.8, younger 2.3±0.9U). The elderly patients using antithrombotic drugs need greater amounts of blood transfusion than younger patients using antithrombotic drugs. The hemoglobin level of the elder patients without antithrombotic drugs was significantly lower than that of younger patients without antithrombotic drugs.
Conclusions:
Our data suggest that our blood transfusion strategy seems to be in tolerance level with restrictive blood transfusion strategy.
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