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The role of embolization for hemangiomas
Andreas F Mavrogenis1, Giuseppe Rossi, Teresa Calabrò
1Department of Orthopaedics, Orthopaedic Oncology Service, Istituto Ortopedico Rizzoli, University of Bologna, Via Di Barbiano 1/10, 40136, Bologna, Italy. afm@otenet.gr
Musculoskeletal Surgery
|June 12, 2012
Summary
N-2-butyl cyanoacrylate embolization effectively relieved pain in most patients with bone and soft-tissue hemangiomas. While bone hemangiomas showed greater ossification and size reduction, soft-tissue hemangiomas had fewer recurrences.
Area of Science:
- Interventional Radiology
- Vascular Malformations
- Oncology
Background:
- Hemangiomas are benign vascular tumors that can cause significant pain and morbidity.
- N-2-butyl cyanoacrylate embolization is a treatment option for symptomatic hemangiomas.
Purpose of the Study:
- To evaluate the efficacy and safety of N-2-butyl cyanoacrylate embolization for painful bone and soft-tissue hemangiomas.
- To assess pain relief, tumor size reduction, ossification, and recurrence rates after embolization.
Main Methods:
- Retrospective study of 31 patients with bone (15) and soft-tissue (16) hemangiomas treated with 39 embolizations.
- N-2-butyl cyanoacrylate was used as the embolic agent.
- Clinical and imaging outcomes were assessed using pain scores, tumor size, and ossification, with a mean follow-up of 47 months.
Main Results:
- Complete pain relief was achieved in 9 bone and 10 soft-tissue hemangioma patients.
- Recurrence of pain occurred in 4 bone and 4 soft-tissue hemangioma patients, requiring repeat embolization.
- Ossification and tumor size reduction were more pronounced in bone hemangiomas.
- Embolization-related complications were more frequent in soft-tissue hemangiomas.
Conclusions:
- N-2-butyl cyanoacrylate embolization is an effective treatment for painful bone and soft-tissue hemangiomas, offering significant pain relief.
- Bone hemangiomas demonstrate better imaging response (ossification, size reduction) compared to soft-tissue hemangiomas.
- While soft-tissue hemangiomas showed no re-recurrences in this study, complications were more common, necessitating careful consideration of the risks and benefits.
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