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Compact Quantum Dots for Single-molecule Imaging
Published on: October 9, 2012
Stable functionalization of small semiconducting polymer dots via covalent cross-linking and their application for
Jiangbo Yu1, Changfeng Wu, Xuanjun Zhang
1Department of Chemistry, University of Washington, Seattle, WA 98195, USA.
Advanced Materials (Deerfield Beach, Fla.)
|June 12, 2012
Abstract:
A facile cross-linking strategy covalently links functional molecules to semiconducting polymer dots (Pdots) while simultaneously providing functional groups for biomolecular conjugation. In addition to greatly enhanced stability, the formed Pdots are small (<10 nm), which can be difficult to achieve with current methods but is highly desirable for most biological applications. These characteristics are significant for improving labeling efficiency and sensitivity in cellular assays that employ Pdots.
