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Update: Cytokine Dysregulation in Chronic Nonbacterial Osteomyelitis (CNO)

Sigrun R Hofmann1, Angela Roesen-Wolff, Gabriele Hahn

  • 1Department of Pediatrics, University Hospital Carl Gustav Carus, Fetscherstra β e 74, 01307 Dresden, Germany.

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Chronic Inflammation: Introduction

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Cytotoxic Edema: Pathophysiology

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Inflammatory Response

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Osteoclasts in Bone Remodeling

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Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...