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Perinatal risk factors and later social, thought, and attention problems after perinatal stroke

Mary J Harbert1, Micaela Jett, Mark Appelbaum

  • 1Department of Neurosciences, University of California San Diego School of Medicine and Rady Children's Hospital-San Diego, La Jolla, CA 92093, USA.

Stroke Research and Treatment
|June 12, 2012
PubMed

Insights

Perinatal stroke survivors face behavioral issues. Key perinatal factors like gestational age and fetal distress are linked to social, thought, and attention problems in children.

Area of Science:

  • Neurology
  • Developmental Pediatrics
  • Child Psychology

Background:

  • Children with perinatal stroke are at risk for behavioral problems.
  • Identifying specific perinatal risk factors for these issues is crucial for early intervention.
  • Understanding these links can improve long-term outcomes for affected children.

Purpose of the Study:

  • To investigate the association between perinatal factors and behavioral problems in children with unilateral perinatal stroke.
  • To identify specific perinatal risk factors that may predict later social, thought, and attention difficulties.
  • To provide data for anticipatory guidance for parents and healthcare providers.

Main Methods:

  • A cohort of 79 children with unilateral perinatal stroke was assessed.
  • Perinatal data collected included gestational age, neonatal seizures, fetal distress, and mode of delivery.
  • Behavioral problems were evaluated using the Achenbach Child Behavior Checklist (CBCL), focusing on Social, Thought, and Attention Problems scales.

Main Results:

  • Lower gestational age and uteroplacental insufficiency correlated with increased Thought Problems.
  • Attention Problems showed a trend towards significance with these factors.
  • Fetal distress, neonatal seizures, or early diagnosis were linked to a 25-30% incidence of clinically significant behavioral issues.

Conclusions:

  • Several perinatal factors are significantly associated with a higher incidence of social, thought, and behavioral problems in children with perinatal stroke.
  • These findings highlight the importance of considering specific perinatal events when assessing behavioral outcomes.
  • This information can aid in providing targeted support and guidance to families and clinicians.

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