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Immunohistochemical staining and malignancies of unknown primary origin

Jennifer Turney1, Phillip Daroca, James Brown

  • 1Department of Surgery and Pathology, Tulane University School of Medicine, New Orleans, USA.

The Journal of the Louisiana State Medical Society : Official Organ of the Louisiana State Medical Society
|June 13, 2012
PubMed
Abstract

No abstract available in PubMed .

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Immunocytochemistry and Immunohistochemistry01:22

Immunocytochemistry and Immunohistochemistry

Immunocytochemistry (ICC) and immunohistochemistry (IHC) are techniques that use antibodies to check for specific proteins or antigens in a sample. The technique was first published by Albert Coons in 1941 to detect the presence of pneumococcal antigen in tissue sections from mice infected with Pneumococcus. Immunocytochemistry helps localization of proteins or antigens in individual cells like blood cells, stem cells, etc., while immunohistochemistry does the same for tissue samples.
These...