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Updated: May 21, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Aggressive periodontitis: the silent tooth killer
1Department of Periodontology, School of Graduate Dentistry, Rambam Health Care Campus and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel. liranl@technion.ac.il
Abstract:
Aggressive periodontitis comprises a group of rapidly progressive forms of periodontitis characterized by early onset of clinical manifestations at a young age and a distinctive tendency for cases to aggregate in families. Though once believed to be a rare condition, recent evidence suggest that aggressive periodontitis is more common than assumed. The etiology of aggressive periodontitis is probably due to the expression of highly virulent causative agents in combination with high levels of susceptibility of the individual patient. In addition, there are several factors, such as cigarette smoking and ethnicity, that are associated with higher prevalence or severity of aggressive periodontitis. Since the disease usually appears at a young age, the importance of early detection is paramount in order to avoid tooth loss in early childhood or adolescence.
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