Related Experiment Video
Updated: May 21, 2026

Stochastic Noise Application for the Assessment of Medial Vestibular Nucleus Neuron Sensitivity In Vitro
Published on: August 28, 2019
Stochastic resonance in Hodgkin-Huxley neuron induced by unreliable synaptic transmission
1School of Electronic Engineering, University of Electronic Science and Technology of China, Chengdu 610054, People's Republic of China. dqguo07@gmail.com
Abstract:
We systematically investigate the stochastic dynamics of a single Hodgkin-Huxley neuron driven by stochastic excitatory and inhibitory input spikes via unreliable synapses in this paper. Based on the mean-filed theory, a novel intrinsic neuronal noise regulation mechanism stemming from unreliable synapses is presented. Our simulation results show that, under certain conditions, the stochastic resonance phenomenon is able to be induced by the unreliable synaptic transmission, which can be well explained by the theoretical prediction. To a certain degree, the results presented here provide insights into the functional roles of unreliable synapses in neural information processing.
Related Concept Videos
Excitatory and Inhibitory Effects of Neurotransmitters
The Role of Ion Channels in Neuronal Computation
Sometimes a single EPSP is strong enough to induce an action potential in the postsynaptic neuron. However, multiple presynaptic inputs must often create EPSPs around the same time for the postsynaptic neuron to be sufficiently depolarized to fire an action potential.
Chemical Synapses
Because chemical synapses depend on the release of neurotransmitter molecules from synaptic vesicles to pass on their signal, there is an approximately one millisecond delay between when the axon potential reaches the presynaptic terminal and when the neurotransmitter leads to opening of postsynaptic ion channels. Additionally, this signaling is...
Chemical Synapses
Because chemical synapses depend on the release of neurotransmitter molecules from synaptic vesicles to pass on their signal, there is an approximately one millisecond delay between when the axon potential reaches the presynaptic terminal and when the neurotransmitter leads to opening of postsynaptic ion channels. Additionally, this signaling is...
Muscle Stimulation Frequency
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
Long-term Potentiation
Hebbian LTP
LTP can occur when presynaptic neurons...

