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Updated: May 21, 2026

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A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
An unusual cause for recurrent transient ischaemic attacks
1Endocrinology Department, East and North Hertfordshire Trust, Welwyn Garden City, UK. bakiejupi@doctors.org.uk
BMJ Case Reports
|June 13, 2012
Summary
Hereditary haemorrhagic telangiectasia (HHT) can cause shortness of breath and transient ischaemic attacks. Definitive treatment of arteriovenous malformations in HHT patients resolves these debilitating symptoms.
Area of Science:
- Cardiology
- Pulmonology
- Neurology
Background:
- Hereditary haemorrhagic telangiectasia (HHT) is a genetic disorder causing abnormal blood vessel formation.
- Patients with HHT can experience significant respiratory and neurological complications.
Observation:
- A 37-year-old male with diagnosed HHT presented with recurrent dyspnea and transient ischemic attacks (TIAs).
- Diagnostic workup included computed tomography pulmonary angiography (CTPA).
Findings:
- CTPA revealed arteriovenous malformations (AVMs) in the pulmonary vasculature.
- Targeted treatment for the AVMs was initiated.
Implications:
- Successful treatment of pulmonary AVMs in HHT patients can lead to complete symptom resolution.
- This case highlights the importance of diagnosing and treating vascular abnormalities in HHT.
- Early intervention can significantly improve patient quality of life and prevent severe complications.
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