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Treatment adherence and blood pressure control in older individuals with hypertension

Rachel G Bastos-Barbosa1, Eduardo Ferriolli, Julio C Moriguti

  • 1Departamento de Medicina Interna, Escola de Medicina, Universidade de São Paulo, Ribeirão Preto, Brazil.

Insights

Treatment adherence in older adults with hypertension was low, but blood pressure control was high, especially when including the white-coat effect. Different adherence measurement tools showed poor agreement, highlighting challenges in assessing patient compliance.

Area of Science:

  • Gerontology
  • Cardiovascular Medicine
  • Public Health

Background:

  • Non-adherence to hypertension treatment is a primary cause of uncontrolled blood pressure (BP).
  • Older individuals may face increased risks associated with uncontrolled BP due to treatment non-adherence.

Purpose of the Study:

  • To evaluate and compare adherence rates to hypertension treatment using various methods.
  • To estimate the blood pressure control rate in older hypertensive patients.
  • To investigate the association between BP control and treatment adherence.

Main Methods:

  • Adherence assessed in older hypertensive patients using Morisky-Green test, Attitude regarding Medication Intake (AMI), Nurse Adherence Evaluation (NAE), and Home Adherence Evaluation (HAE).
  • Salt intake estimated via 24-hour urinary sodium excretion.
  • Blood pressure control measured by awake ambulatory blood pressure monitoring.

Main Results:

  • Poor concordance observed between Morisky-Green test and AMI (Kappa=0.27) or NAE (Kappa=0.05); moderate concordance with HAE.
  • Eighty percent of patients achieved controlled BP, with 42% exhibiting the white-coat effect.
  • Lower salt excretion group showed better medication adherence (p<0.001) and reported salt avoidance more frequently (p<0.001).

Conclusions:

  • Existing adherence assessment tools demonstrated poor agreement with the reference Morisky-Green test.
  • Hypertension treatment adherence was generally low among the study population.
  • High BP control rates were achieved, particularly when including patients with the white-coat effect.
Abstract

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