Related Experiment Videos
Treatment adherence and blood pressure control in older individuals with hypertension
Rachel G Bastos-Barbosa1, Eduardo Ferriolli, Julio C Moriguti
1Departamento de Medicina Interna, Escola de Medicina, Universidade de São Paulo, Ribeirão Preto, Brazil.
Insights
Treatment adherence in older adults with hypertension was low, but blood pressure control was high, especially when including the white-coat effect. Different adherence measurement tools showed poor agreement, highlighting challenges in assessing patient compliance.
Area of Science:
- Gerontology
- Cardiovascular Medicine
- Public Health
Background:
- Non-adherence to hypertension treatment is a primary cause of uncontrolled blood pressure (BP).
- Older individuals may face increased risks associated with uncontrolled BP due to treatment non-adherence.
Purpose of the Study:
- To evaluate and compare adherence rates to hypertension treatment using various methods.
- To estimate the blood pressure control rate in older hypertensive patients.
- To investigate the association between BP control and treatment adherence.
Main Methods:
- Adherence assessed in older hypertensive patients using Morisky-Green test, Attitude regarding Medication Intake (AMI), Nurse Adherence Evaluation (NAE), and Home Adherence Evaluation (HAE).
- Salt intake estimated via 24-hour urinary sodium excretion.
- Blood pressure control measured by awake ambulatory blood pressure monitoring.
Main Results:
- Poor concordance observed between Morisky-Green test and AMI (Kappa=0.27) or NAE (Kappa=0.05); moderate concordance with HAE.
- Eighty percent of patients achieved controlled BP, with 42% exhibiting the white-coat effect.
- Lower salt excretion group showed better medication adherence (p<0.001) and reported salt avoidance more frequently (p<0.001).
Conclusions:
- Existing adherence assessment tools demonstrated poor agreement with the reference Morisky-Green test.
- Hypertension treatment adherence was generally low among the study population.
- High BP control rates were achieved, particularly when including patients with the white-coat effect.
Background:
Non-adherence to treatment has been identified as the main cause of uncontrolled blood pressure (BP), and may represent a greater risk in older individuals.
Objective:
The aim of this study was to evaluate and compare the rate of adherence to hypertension treatment using different methods, to estimate the BP control rate, and to observe if there is an association between BP control and adherence.
Methods:
Treatment adherence was evaluated in older patients with hypertension, followed by the public primary health care, through four methods, including the Morisky-Green test (reference), the Attitude regarding the Medication Intake questionnaire (AMI), an evaluation of adherence by the nurse in the office (Nurse Adherence Evaluation - NAE), and at home (Home Adherence Evaluation - HAE). Salt intake was estimated by 24-hour sodium urinary excretion. BP control was assessed by the awake ambulatory blood pressure monitoring.
Results:
Concordance between the Morisky-Green test and AMI (Kappa=0.27) or NAE (Kappa=0.05) was poor. There was a moderate concordance between the Morisky-Green test and HAE. Eighty percent had controlled BP, including 42% with white-coat effect. The group with lower salt excretion informed to avoid salt intake more times (p<0.001) and had better medication adherence (p<0.001) than the higher salt excretion group.
Conclusion:
The evaluated tests did not show a good concordance to the Morisky-Green test. Adherence to hypertension treatment was low; however, there was a high rate of BP control when subjects with the white-coat effect were included in the analysis.
Related Concept Videos
Hypertension V: Nursing Management
Hypertension IV: Drug Therapy and Lifestyle Modifications
Hypertension III: Clinical Manifestations and Diagnostic Studies
Errors occurring during blood pressure monitoring
Several factors...
Drug Dosing: Geriatric Patients
Hypertension and Regulation of Blood Pressure