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Published on: December 23, 2022
Whole-genome sequence of Stenotrophomonas maltophilia D457, a clinical isolate and a model strain
Felipe Lira1, Alvaro Hernández, Eugeni Belda
1Departamento de Biotecnología Microbiana, Centro Nacional de Biotecnología, CSIC, Madrid, Spain.
Abstract:
Stenotrophomonas maltophilia is an opportunistic pathogen with an environmental origin, and it is an increasingly relevant cause of nosocomial infections. Here we present the whole-genome sequence of S. maltophilia strain D457, a clinical isolate that is being used as a model for studying antibiotic resistance in this bacterial species.
Insights
Stenotrophomonas maltophilia, a nosocomial infection cause, has its whole-genome sequenced. This strain D457 provides a model for understanding antibiotic resistance in this opportunistic pathogen.
Area of Science:
- Microbiology
- Genomics
- Infectious Diseases
Background:
- Stenotrophomonas maltophilia is an opportunistic pathogen originating from the environment.
- It is a growing cause of hospital-acquired (nosocomial) infections.
Purpose of the Study:
- To present the whole-genome sequence of Stenotrophomonas maltophilia strain D457.
- To establish strain D457 as a model for studying antibiotic resistance in S. maltophilia.
Main Methods:
- Whole-genome sequencing of the clinical isolate S. maltophilia strain D457.
Main Results:
- The complete genome sequence of S. maltophilia strain D457 has been determined.
Conclusions:
- The genome sequence of strain D457 will facilitate research into S. maltophilia's antibiotic resistance mechanisms.
- This resource supports the development of strategies to combat nosocomial infections caused by this pathogen.
