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Related Concept Videos

Hedgehog Signaling Pathway02:33

Hedgehog Signaling Pathway

The Hedgehog gene (Hh) was first discovered due to its control of the growth of disorganized, hair-like bristles phenotype in Drosophila, much like hedgehog spines. Hh plays a crucial role in the development of organs and the maintenance of homeostasis in both invertebrates and vertebrates. However, while Drosophila has only one Hh protein, mammals have multiple functional Hedgehog proteins - Sonic (Shh), Desert (Dhh), and Indian Hedgehog (Ihh). All of these homologous proteins have adapted to...
Hedgehog Signaling Pathway02:33

Hedgehog Signaling Pathway

The Hedgehog gene (Hh) was first discovered due to its control of the growth of disorganized, hair-like bristles phenotype in Drosophila, much like hedgehog spines. Hh plays a crucial role in the development of organs and the maintenance of homeostasis in both invertebrates and vertebrates. However, while Drosophila has only one Hh protein, mammals have multiple functional Hedgehog proteins - Sonic (Shh), Desert (Dhh), and Indian Hedgehog (Ihh). All of these homologous proteins have adapted to...
Assembly of Signaling Complexes01:30

Assembly of Signaling Complexes

Multiprotein signaling complexes are formed in a dynamic process involving protein-protein interactions at the cytoplasmic domain of transmembrane receptors or enzymatic and non-enzymatic proteins associated with the receptor. These complexes ensure the activation and propagation of intracellular signals that regulate cell functions.
Interaction domains in cell signaling
Interaction domains recognize exposed features of their binding partners containing post-translationally modified sequences,...
Chemical Signaling in the Endocrine System01:08

Chemical Signaling in the Endocrine System

A signaling cascade is a series of events that facilitates the transmission of information within or between cells, culminating in a targeted response in the recipient cell. As chemical messengers, hormones are pivotal in initiating and modulating these intricate signaling cascades based on their solubility.
Lipid-soluble hormones, such as steroid hormones, demonstrate an intracellular action. These hormones traverse cell membranes due to their lipid nature. Once inside the target cell, they...
Endocrine Signaling01:45

Endocrine Signaling

Endocrine cells produce hormones to communicate with remote target cells found in other organs. The hormone reaches these distant areas using the circulatory system. This exposes the whole organism to the hormone but only those cells expressing hormone receptors or target cells are affected. Thus, endocrine signaling induces slow responses from its target cells but these effects also last longer.
Endocrine Signaling01:45

Endocrine Signaling

Endocrine cells produce hormones to communicate with remote target cells found in other organs. The hormone reaches these distant areas using the circulatory system. This exposes the whole organism to the hormone but only those cells expressing hormone receptors or target cells are affected. Thus, endocrine signaling induces slow responses from its target cells but these effects also last longer.

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Related Experiment Video

Updated: May 21, 2026

Measuring Glutathione-induced Feeding Response in Hydra
08:10

Measuring Glutathione-induced Feeding Response in Hydra

Published on: November 16, 2014

Peptide signaling in Hydra.

Toshitaka Fujisawa1, Eisuke Hayakawa

  • 1Department of Developmental Genetics, National Institute of Genetics, Mishima, Japan. tfujisaw@ims.ac.jp

The International Journal of Developmental Biology
|June 13, 2012
PubMed
Summary

Researchers identified numerous peptide signaling molecules in Hydra, a basal metazoan. This study details their genes, functions, and evolutionary origins, advancing our understanding of peptide signaling systems.

Area of Science:

  • * Molecular Biology
  • * Evolutionary Biology
  • * Zoology

Background:

  • * Peptides are vital signaling molecules in metazoans.
  • * Understanding peptide roles in basal organisms like Cnidaria is crucial for evolutionary insights.
  • * The

Purpose of the Study:

  • * To systematically identify peptide signaling molecules, their encoding genes, and functions in Hydra magnipapillata.
  • * To investigate the synthesis, processing, and release mechanisms of these peptides.
  • * To explore the evolution of peptide signaling systems in cnidarians.

Main Methods:

  • * Peptidomic approach for systematic identification of peptides.
  • * Analysis of gene sequences encoding identified peptides.

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Generation and Long-term Maintenance of Nerve-free Hydra

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Related Experiment Videos

Last Updated: May 21, 2026

Measuring Glutathione-induced Feeding Response in Hydra
08:10

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Published on: November 16, 2014

Generation of Transgenic Hydra by Embryo Microinjection
09:10

Generation of Transgenic Hydra by Embryo Microinjection

Published on: September 11, 2014

Generation and Long-term Maintenance of Nerve-free Hydra
06:33

Generation and Long-term Maintenance of Nerve-free Hydra

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  • * Functional characterization of peptide signaling molecules.

    • Main Results:

    • * Identification of numerous peptide signaling molecules in Hydra and other cnidarians.
    • * Detailed reporting of peptide synthesis, processing, and release pathways.
    • * Overview of potential peptide signaling pathways.

    Conclusions:

    • * The study provides a comprehensive catalog of peptides in Hydra, contributing to the