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Updated: May 21, 2026

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
Published on: June 14, 2021
Spontaneous resolution of full-thickness macular hole in retinitis pigmentosa
Muhammad Raja1, Craig Goldsmith, Benjamin J L Burton
1Ophthalmology Department, James Paget University Hospital, NHS Foundation Trust, Great Yarmouth, Norfolk, UK. docraja@hotmail.com
Abstract:
A 57-year-old woman, diagnosed with retinitis pigmentosa and positive family history, was referred to the retinal clinic. Full-thickness macular hole was noted in the right eye with no significant vitreomacular interface abnormalities confirmed at baseline visit with spectral-domain optical coherence tomography scan. Routine follow-up showed spontaneous closure of the full-thickness macular hole with four-letter improvement from baseline visit and remains unchanged with 3 years of follow-up.
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