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The Clinical Application of Tumor Treating Fields Therapy in Glioblastoma
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Published on: April 16, 2019

Late and prolonged pseudoprogression in glioblastoma after treatment with lomustine and temozolomide

Moritz Stuplich1, Dariusch R Hadizadeh, Klaus Kuchelmeister

  • 1Division of Clinical Neurooncology, Department of Neurology, University of Bonn Medical Center, Sigmund-Freud-Strasse 25, Bonn, Germany.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
|June 13, 2012
PubMed
Abstract

No abstract available in PubMed .

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Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...