Jove
Visualize
Contact Us

Related Experiment Videos

Polycystic ovary syndrome.

D R Shelley1, A Dunaif

  • 1Department of Medicine, Mount Sinai Medical Center, New York, NY 10029.

Comprehensive Therapy
|November 1, 1990
PubMed
Summary

Polycystic ovary syndrome (PCOS) is a complex endocrine disorder causing irregular ovulation and excess androgens. Diagnosis involves excluding other conditions, with treatment focusing on symptom management and reducing cancer risk.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Functional analysis of rare anti-Müllerian hormone protein-altering variants identified in women with PCOS.

Molecular human reproduction·2023
Same author

An analysis of adaptations to multi-level intervention strategies to enhance implementation of clinical practice guidelines for treating tobacco use in dental care settings.

Contemporary clinical trials communications·2018
Same author

Evidence for gonadotrophin secretory and steroidogenic abnormalities in brothers of women with polycystic ovary syndrome.

Human reproduction (Oxford, England)·2014
Same author

Fine mapping of genetic susceptibility to polycystic ovary syndrome on chromosome 19p13.2 and tests for regulatory activity.

The Journal of clinical endocrinology and metabolism·2006
Same author

Candidate gene region for polycystic ovary syndrome on chromosome 19p13.2.

The Journal of clinical endocrinology and metabolism·2005
Same author

Prevalence and predictors of dyslipidemia in women with polycystic ovary syndrome.

The American journal of medicine·2002
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Area of Science:

  • Reproductive endocrinology
  • Gynecology

Background:

  • Polycystic ovary syndrome (PCOS) is a common endocrine disorder.
  • It is characterized by anovulation, hyperandrogenism, and hormonal imbalances.
  • Hyperinsulinemia and insulin resistance are key features of PCOS.

Purpose of the Study:

  • To define the characteristics of PCOS.
  • To outline diagnostic criteria, emphasizing its nature as a diagnosis of exclusion.
  • To detail treatment strategies for managing PCOS symptoms.

Main Methods:

  • Diagnosis relies on excluding other causes of androgen excess.
  • Clinical and biochemical findings are assessed.
  • Treatment approaches are guided by symptom presentation.

Main Results:

  • PCOS presents with anovulation or oligo-ovulation.
  • Hyperandrogenism is a hallmark of the syndrome.
  • Insulin resistance and hyperinsulinemia are significant contributing factors.

Conclusions:

  • PCOS requires exclusion of other conditions for diagnosis.
  • Treatment aims to alleviate hyperandrogenism, manage obesity, and regulate menses.
  • Effective management reduces the risk of endometrial cancer.

Related Experiment Videos