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A new bromobenzyl methyl sulphoxide from marine red alga Symphyocladia latiuscula
Xiuli Xu1, Liyuan Yin, Yinghui Wang
1School of Ocean Sciences, China University of Geosciences, Beijing 100083, P.R. China. xuxl@cugb.edu.cn
Abstract:
A new bromophenol, 2,3,6-tribromo-4,5-dihydroxybenzyl methyl sulphoxide, was isolated from the EtOH extract of the marine alga Symphyocladia latiuscula. Its structure was confirmed by spectroscopic methods (1D- and 2D-NMR, HR-ESI-MS). This new bromophenol showed moderate antifungal activity against Candida albicans with MIC value of 37.5 µg mL(-1).
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Consider the bromination of cyclopentene. Molecular bromine is polarized in the proximity of the π electrons of cyclopentene. An electrophilic bromine atom adds across the double bond, forming a cyclic bromonium ion intermediate.

