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TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients

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Published on: April 13, 2021

Building sustainable multi-functional prospective electronic clinical data systems.

Gurvaneet S Randhawa¹, Jean R Slutsky

¹Center for Outcomes and Evidence, Agency for Healthcare Research and Quality, Rockville, MD 20850, USA. gurvaneet.randhawa@ahrq.hhs.gov

|June 14, 2012

Summary

This summary is machine-generated.

Aligning biomedical research and healthcare delivery is crucial for understanding real-world clinical intervention impacts. Initiatives are building electronic data infrastructure to support comparative effectiveness research (CER) and improve patient outcomes.

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Area of Science:

Health Services Research
Biomedical Informatics
Comparative Effectiveness Research

Background:

Significant gaps exist in understanding clinical intervention impacts on real-world patient outcomes.
Alignment between biomedical research and healthcare delivery systems is needed to address these knowledge gaps.
Patient outcomes research requires integrated data infrastructure.

Purpose of the Study:

To describe initiatives aimed at aligning biomedical research and healthcare delivery.
To highlight the development of flexible, prospective clinical electronic data infrastructure.
To support comparative effectiveness research (CER) and other health data applications.

Main Methods:

Agency for Healthcare Research and Quality (AHRQ) has supported distributed research networks for CER.
Leveraging experience from previous networks to direct American Recovery and Reinvestment Act (ARRA) funds for CER.
Funding new clinical electronic infrastructure projects for multiple uses.
Establishing an Electronic Data Methods forum to advance informatics and analytics.

Main Results:

Development of prospective clinical electronic data infrastructure to meet diverse user needs.
Creation of distributed research networks enabling CER while protecting patient confidentiality and organizational data.
Support for ARRA-funded projects utilizing electronic infrastructure for CER, quality improvement, clinical decision support, and disease surveillance.
Establishment of a forum to foster collaboration and advance methods in clinical informatics and research analytics.

Conclusions:

Improved alignment and robust electronic data infrastructure are essential for advancing real-world evidence generation.
Initiatives supported by AHRQ are creating valuable resources for CER and improving healthcare quality.
Continued advancement in clinical informatics, analytics, and governance is critical for maximizing the utility of health data.