Related Experiment Video
Updated: May 21, 2026

07:57
An Experimental Human DIEP Flap Model to Investigate Preservation Strategies for Vascularized Composite Allografts and Free Flaps
Published on: December 5, 2025
Vulva reconstruction after pelvic exenteration, using a unique combination of two flaps
Annelotte C M van Bommel1, Henk W R Schreuder, Pascal P A Schellekens
1Department of Plastic and Reconstructive Surgery, University Medical Centre, Utrecht, Netherlands.
BMJ Case Reports
|June 14, 2012
Summary
This study presents a unique surgical reconstruction for recurrent vulvar cancer using a combined anterolateral thigh (ALT) flap and rectus abdominis muscle (RAM) flap. This approach offers excellent results for large, irradiated pelvic defects.
Area of Science:
- Surgical Oncology
- Reconstructive Surgery
- Gynecologic Oncology
Background:
- Recurrent vulvar cancer in irradiated areas presents significant reconstructive challenges.
- Total pelvic exenteration is a radical surgical option for advanced or recurrent pelvic malignancies.
- Large pelvic defects often require well-vascularized tissue for successful reconstruction.
Observation:
- A 64-year-old woman with recurrent vulvar carcinoma underwent en-bloc total pelvic exenteration.
- Pelvic defect reconstruction utilized a combined anterolateral thigh (ALT) flap and a rectus abdominis muscle (RAM) flap (PM/RAM).
- This specific combination of flaps was employed for a large, previously irradiated pelvic defect.
Findings:
- The combined ALT and PM/RAM flap technique provided a unique and effective solution for extensive pelvic reconstruction.
- This dual-flap approach leveraged the reliable vascularity of the PM/RAM flap with the bulk of the ALT flap.
- Excellent reconstructive results were achieved using this innovative flap combination.
Implications:
- This combined flap strategy offers a viable option for complex pelvic defect reconstruction in challenging oncologic cases.
- The synergistic use of ALT and PM/RAM flaps may improve outcomes in patients requiring extensive pelvic resections.
- Further research into optimizing multi-flap combinations for pelvic reconstruction is warranted.