Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Imaging Biomarkers To Predict Progression of Intermediate AMD with Avascular Pigment Epithelial Detachment in the University of Colorado AMD Registry.

Research square·2026

Same author

Menopausal Hormone Therapy and Conversion from Intermediate to Advanced Age-Related Macular Degeneration.

Journal of vitreoretinal diseases·2026

Same author

Probiotic <i>Bacillus subtilis</i>, but Not a <i>Lactobacillus</i> spp., Ameliorates Cognitive Impairment in a Mouse Model of LPS and Zidovudine-Induced Neuroinflammation.

Brain sciences·2026

Same author

Uncertainty-Aware Training for Ophthalmic Segmentation Using MedSAM.

Translational vision science & technology·2026

Same author

Comparing Interactive Machine Learning and Unassisted Segmentation of Geographic Atrophy From Fundus Autofluorescence.

Translational vision science & technology·2026

Same author

Visual functioning and geographic atrophy imaging characteristics in age-related macular degeneration.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2025

Search research articles

Related Experiment Video

Updated: May 21, 2026

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Published on: June 14, 2021

23-gauge vitrectomy for retained lens material.

Ramanath Bhandari¹, Benjamin J Ernst, Ksenia Stafeeva

¹Department of Ophthalmology, Health Science Center, Rocky Mountain Lions Eye Institute, University of Colorado School of Medicine, Aurora, CO 80045, USA. ramanath.bhandari@gmail.com

Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye

|June 14, 2012

Summary

This summary is machine-generated.

This study presents a novel vitrectomy technique for removing retained lens fragments. The method effectively clears dense nuclear and cortical material without requiring a fragmatome, improving surgical outcomes.

More Related Videos

A Step by Step Protocol for Subretinal Surgery in Rabbits

A Step by Step Protocol for Subretinal Surgery in Rabbits

Published on: September 13, 2016

Implantation Protocol of the Foldable Capsular Vitreous Body for Complex Vitreoretinal Surgery

Implantation Protocol of the Foldable Capsular Vitreous Body for Complex Vitreoretinal Surgery

Published on: April 14, 2026

Related Experiment Videos

Last Updated: May 21, 2026

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Published on: June 14, 2021

A Step by Step Protocol for Subretinal Surgery in Rabbits

A Step by Step Protocol for Subretinal Surgery in Rabbits

Published on: September 13, 2016

Implantation Protocol of the Foldable Capsular Vitreous Body for Complex Vitreoretinal Surgery

Implantation Protocol of the Foldable Capsular Vitreous Body for Complex Vitreoretinal Surgery

Published on: April 14, 2026

Area of Science:

Ophthalmology
Surgical Techniques
Retinal Surgery

Background:

Retained lens material after cataract surgery can lead to complications.
Current methods for removal may require specialized equipment like a fragmatome.

Purpose of the Study:

To describe a novel technique for removing retained lens material using a standard vitrectomy system.
To evaluate the efficacy of this technique in clearing dense nuclear and cortical fragments.

Main Methods:

A three-port 23-gauge vitrectomy system was employed.
Core and cortical vitreous were removed, followed by clearing of vitreous adhesions to the lens.
Vitrectomy settings were adjusted (cut rate 1,500 cpm, vacuum 600 mm Hg) for fragment removal.
Cortical and nuclear lens material were removed using the vitrectomy probe and a light pipe for fragment manipulation.

Main Results:

The described technique successfully removed large, dense nuclear and cortical retained lens material.
No need for a fragmatome was identified during the procedure.
Efficient clearance of lens fragments from the vitreous chamber was achieved.

Conclusions:

This vitrectomy-based technique offers a viable alternative for managing retained lens material.
It simplifies the surgical procedure by eliminating the need for additional instrumentation.
The method is effective even for challenging, dense lens fragments.