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Recurrent Microvirgula aerodenitrificans bacteremia
Michael E Murphy1, Angus Goodson, Henry Malnick
1Department of Clinical Microbiology, Buckinghamshire Healthcare NHS Trust, Aylesbury, Buckinghamshire, United Kingdom.
Journal of Clinical Microbiology
|June 14, 2012
Summary
Microvirgula aerodenitrificans, a denitrifying bacterium, has been identified as the cause of bacteremia in a human infant. This marks the first reported clinical infection by this globally isolated organism.
Area of Science:
- Microbiology
- Clinical Microbiology
- Infectious Diseases
Background:
- Microvirgula aerodenitrificans is a Gram-negative, denitrifying bacterium.
- First described in 1998, it has been isolated worldwide.
- Previously, M. aerodenitrificans was not known to cause human infections.
Observation:
- A case of bacteremia in an infant is reported.
- The infant had a history of Pompe's disease.
- Microvirgula aerodenitrificans was identified as the causative agent.
Findings:
- This is the first documented human infection caused by Microvirgula aerodenitrificans.
- The study details the clinical presentation and identification of the bacterium.
- The infant's underlying condition, Pompe's disease, may have predisposed them to infection.
Implications:
- Highlights the potential for previously non-pathogenic organisms to cause clinical disease.
- Suggests the need for broader consideration of M. aerodenitrificans in differential diagnoses.
- Emphasizes the importance of identifying rare bacterial pathogens in vulnerable populations.
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