Related Experiment Video
Updated: May 21, 2026

Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis
Published on: October 12, 2016
Superior fixation of machine-made bone pegs over handmade bone pegs
Shinji Imade1, Yuji Uchio, Nobuaki Ozoe
1Department of Orthopaedic Surgery, Faculty of Medicine, Shimane University School of Medicine, Izumo, Shimane, Japan. imades@med.shimane-u.ac.jp
Background:
Bone pegs are one of the best devices to treat an intra-articular lesion with fragments because of the pegs' biological characteristics, but the initial strength of the fragment fixation in these cases is unknown. In addition, the relationship between the geometry of bone pegs and the strength of fragment fixation remains unknown. We hypothesized that a microscopically fine bone peg made by a precision machine can provide a higher level of strength than that of a macroscopically fine bone peg made by hand both initially and postoperatively.
Methods:
The machine-made bone pegs were made from cortical bone of cattle by a precision machine, and the handmade bone pegs were made by hand using the same material. An osteochondral lesion model was made, and two pegs of the same type were inserted to fix each test fragment. The shearing and pull-out strength of the fragment were investigated in both types of peg. Next, both types of peg were inserted into a hole made in the distal femur of a rabbit, and 10 days later, mechanical tests were performed.
Results:
The machine-made bone pegs were initially twice as strong as the handmade bone pegs, and they were 1.4 times as strong as the handmade bone pegs at 10 days after surgery.
Conclusion:
We recommend that bone pegs be made by machining rather than by hand. The machine-made bone pegs have the potential to ensure early postoperative rehabilitation.
Related Concept Videos
Sutures of the Skull
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Structural Joints: Fibrous Joints
Suture
All the bones of the skull, except for the mandible, are joined to each other by a fibrous joint called a suture. The fibrous connective tissue found at a suture strongly unites the adjacent skull bones and thus helps to protect the brain and form the face. In...

