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Moyamoya disease-related versus primary intracerebral hemorrhage: [corrected] location and outcomes are different

Hyun-Wook Nah1, Sun U Kwon, Dong-Wha Kang

  • 1Department of Neurology, University of Ulsan, Asan Medical Center, 388-1 Pungnap-dong, Songpa-gu, Seoul 138-736, Korea.

Stroke
|June 14, 2012
PubMed
Abstract

Insights

Moyamoya disease-related intracerebral hemorrhage often presents as intraventricular bleeding, unlike primary intracerebral hemorrhage. Patients with moyamoya disease face higher risks of rebleeding and infarction.

Area of Science:

  • Neurology
  • Neuroimaging
  • Cerebrovascular Diseases

Background:

  • Moyamoya disease-related intracerebral hemorrhage (MMD-ICH) and primary intracerebral hemorrhage (P-ICH) are distinct conditions.
  • Understanding their differences is crucial for diagnosis and treatment.

Purpose of the Study:

  • To compare the lesion location of MMD-ICH with P-ICH.
  • To investigate the association between hemorrhage location and angiographic findings in MMD-ICH.

Main Methods:

  • A comparative study involving 93 patients each with MMD-ICH and P-ICH.
  • Assessment of angiographic findings, focusing on the anterior choroidal artery in MMD-ICH.
  • Follow-up through clinical visits and telephone interviews.

Main Results:

  • Hemorrhage location significantly differed between MMD-ICH (intraventricular: 37.6%) and P-ICH (putaminal: 46.2%).
  • Intraventricular hemorrhage was more common in MMD-ICH (80.6%) than P-ICH (20.4%).
  • A prominent anterior choroidal artery was associated with primary intraventricular hemorrhage in MMD-ICH (75.0%).
  • MMD-ICH patients exhibited higher rates of rebleeding and infarction compared to P-ICH.

Conclusions:

  • MMD-ICH characteristically presents with intraventricular hemorrhage, potentially linked to a prominent anterior choroidal artery.
  • Patients with MMD-ICH have an increased likelihood of recurrent bleeding and infarction.

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