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Related Concept Videos

Gastritis II: Pathophysiology01:26

Gastritis II: Pathophysiology

The pathophysiology of gastritis begins with the colonization of the stomach lining by Helicobacter pylori (H. pylori). This bacterium spreads mainly via the oral-oral route through saliva or shared utensils, and can also be transmitted in overcrowded or unhygienic environments through contaminated water, despite its brief survival outside the body.ColonizationOnce ingested, H. pylori enters the stomach and begins colonization by navigating through the mucus layer lining the stomach wall. It...
Pyloric Obstruction01:11

Pyloric Obstruction

Pyloric obstruction, also referred to as gastric outlet obstruction, is a condition characterized by narrowing or blockage at the pylorus—the muscular valve regulating the flow of stomach contents into the duodenum. When this passage becomes impaired, the stomach cannot effectively empty its contents into the small intestine. This disruption leads to a range of gastrointestinal symptoms, including early satiety, bloating, epigastric pain, postprandial nausea, persistent vomiting, and...
Gastritis-I: Introduction and Types01:27

Gastritis-I: Introduction and Types

Gastritis, defined by the inflammation or irritation of the stomach lining or gastric mucosa, manifests in several distinct forms: acute, chronic, reactive, and a specific subtype known as autoimmune metaplastic atrophic gastritis.
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...
Peptic Ulcer Disease III: Clinical Manifestations and Complications01:25

Peptic Ulcer Disease III: Clinical Manifestations and Complications

Duodenal UlcersDuodenal ulcers are the most common form of peptic ulcer disease, presenting with chronic, intermittent epigastric pain. Pain typically appears 2–3 hours after meals, especially when the stomach is empty, often waking patients at night. It is characteristically relieved by food or antacids (“pain–food–relief”). Some patients remain asymptomatic until complications like bleeding or perforation emerge, particularly with NSAID or anticoagulant use.Gastric UlcersGastric ulcers share...
Gastritis III: Clinical Manifestations and Management01:23

Gastritis III: Clinical Manifestations and Management

The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Peptic Ulcer01:27

Peptic Ulcer

Peptic ulcers are erosive lesions of the gastric or duodenal lining, most commonly caused by Helicobacter pylori infection. This Gram-negative, helical bacterium has adapted to survive the stomach’s acidic environment by producing urease, which converts urea into ammonia and carbon dioxide. The ammonia neutralizes gastric acid in the bacterium’s immediate environment, allowing colonization of the gastric mucosa. H. pylori attaches to mucus-secreting epithelial cells, penetrates the mucus...

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Related Experiment Video

Updated: May 21, 2026

Single Incision Plus One Port Laparoscopic Proximal Gastrectomy with Double Channel Anastomosis for Gastric Cancer Treatment
03:32

Single Incision Plus One Port Laparoscopic Proximal Gastrectomy with Double Channel Anastomosis for Gastric Cancer Treatment

Published on: December 27, 2024

Gastric carcinoma-a rare presentation.

Syam Vikram, Pradeep Jacob, C Gopalakrishnan Nair

    Indian Journal of Surgical Oncology
    |June 14, 2012
    PubMed
    Summary

    Idiopathic deep vein thrombosis (IDVT) is strongly linked to hidden cancers, affecting 4-25% of patients. Screening for malignancy is recommended in all IDVT cases to improve patient outcomes.

    Area of Science:

    • Oncology
    • Vascular Medicine
    • Internal Medicine

    Background:

    • Idiopathic deep vein thrombosis (IDVT) is increasingly associated with occult (hidden) malignancies.
    • Literature reviews indicate this association occurs in 4-25% of IDVT cases.
    • This association necessitates screening for underlying cancer in patients with IDVT.

    Observation:

    • A case of advanced gastric carcinoma presented with an unusual manifestation.
    • The patient experienced upper limb deep vein thrombosis (DVT).
    • Pulmonary embolism was also identified as a complication.

    Findings:

    • The gastric carcinoma was initially occult, presenting solely as DVT and pulmonary embolism.
    • This case highlights the potential for gastrointestinal cancers to manifest initially as venous thromboembolism.
    Keywords:
    Idiopathic deep vein thrombosisoccult gastricpulmonary embolism

    Related Experiment Videos

    Last Updated: May 21, 2026

    Single Incision Plus One Port Laparoscopic Proximal Gastrectomy with Double Channel Anastomosis for Gastric Cancer Treatment
    03:32

    Single Incision Plus One Port Laparoscopic Proximal Gastrectomy with Double Channel Anastomosis for Gastric Cancer Treatment

    Published on: December 27, 2024

  • The diagnosis of gastric cancer was established following the DVT presentation.

    • Implications:

    • Early screening for malignancy in IDVT patients can lead to earlier cancer diagnosis.
    • Prompt diagnosis and treatment of occult cancers associated with DVT may improve prognosis.
    • This case underscores the importance of considering malignancy in the differential diagnosis of unexplained DVT, particularly in the upper extremities.