Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Southern Blot02:57

Southern Blot

Agarose gel electrophoresis is very useful in separating DNA fragments by size. Running a DNA ladder containing fragments of the known length alongside the sample helps determine the approximate length of the sample DNA fragments. However, additional steps are needed to verify the sequence identity of the sample DNA fragments.
Denatured DNA fragments must be transferred onto a carrier membrane from the gel to make it accessible to a probe - a small ssDNA fragment complementary to the target DNA...
Mass Spectrometry: Complex Analysis01:21

Mass Spectrometry: Complex Analysis

Mass spectrometry is an important technique for the identification of pure compounds. However, it has some limitations for the analysis of complex mixtures, often due to excessive fragmentation making the spectrum too complicated to decipher. Mass spectrometry can be combined with suitable separation methods in sequence, forming hyphenated methods, which are useful in the analysis of complex mixtures.
GC–MS is a powerful hyphenated method commonly used in forensics and environmental...
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
Methods of Classification and Identification01:28

Methods of Classification and Identification

Bacterial identification relies on a diverse array of techniques to classify and understand microorganisms, each tailored to uncover specific characteristics. Traditional morphological approaches, while still valuable, are limited for closely related or structurally simple organisms. Modern methods integrate biochemical, serological, genetic, and advanced molecular tools to achieve greater accuracy.Morphological and Biochemical TechniquesMorphological characteristics, such as cell shape and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Epigenetic consequences of toxic stress in preterm infants and their mothers: protocol for the premature infants, moms, and the social determinants of health-an epigenetic investigation study.

Frontiers in pediatrics·2026
Same author

The association between prescribed hormonal contraception and multiple sclerosis risk: a systematic review and meta-analysis.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026
Same author

Antimicrobial Loaded Graft-Copolymer Nanoparticles for Treatment of <i>Pseudomonas aeruginosa</i> Infections.

bioRxiv : the preprint server for biology·2025
Same author

Act fast, stop COVID: The successful implementation of the first decentralised Victorian COVID-19 contact tracing and monitoring unit.

Australian and New Zealand journal of public health·2024
Same author

Changes in injury and illness incidence and burden in elite junior male Australian footballers over a 6-year period.

Journal of science and medicine in sport·2024
Same author

A genome-wide association study to investigate genetic loci associated with primary glaucoma in American Cocker Spaniels.

American journal of veterinary research·2022

Related Experiment Video

Updated: May 21, 2026

Enhanced Genetic Analysis of Single Human Bioparticles Recovered by Simplified Micromanipulation from Forensic &#8216;Touch DNA&#8217; Evidence
11:49

Enhanced Genetic Analysis of Single Human Bioparticles Recovered by Simplified Micromanipulation from Forensic ‘Touch DNA’ Evidence

Published on: March 9, 2015

Forensic DNA analysis.

Jessica McDonald1, Donald C Lehman

  • 1Department of Medical Technology. University of Delaware, Newark, DE 19716, USA.

Clinical Laboratory Science : Journal of the American Society for Medical Technology
|June 15, 2012
PubMed
Summary
This summary is machine-generated.

Forensic blood typing is no longer routine due to its limited discrimination. DNA profiling is now the standard for forensic analysis, offering superior identification capabilities.

More Related Videos

Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes
08:35

Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes

Published on: July 17, 2021

A Noninvasive Hair Sampling Technique to Obtain High Quality DNA from Elusive Small Mammals
07:40

A Noninvasive Hair Sampling Technique to Obtain High Quality DNA from Elusive Small Mammals

Published on: March 13, 2011

Related Experiment Videos

Last Updated: May 21, 2026

Enhanced Genetic Analysis of Single Human Bioparticles Recovered by Simplified Micromanipulation from Forensic &#8216;Touch DNA&#8217; Evidence
11:49

Enhanced Genetic Analysis of Single Human Bioparticles Recovered by Simplified Micromanipulation from Forensic ‘Touch DNA’ Evidence

Published on: March 9, 2015

Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes
08:35

Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes

Published on: July 17, 2021

A Noninvasive Hair Sampling Technique to Obtain High Quality DNA from Elusive Small Mammals
07:40

A Noninvasive Hair Sampling Technique to Obtain High Quality DNA from Elusive Small Mammals

Published on: March 13, 2011

Area of Science:

  • Forensic Science
  • Genetics
  • Biotechnology

Background:

  • Blood typing was a primary forensic tool before DNA profiling.
  • Blood typing lacks discriminatory power, with common blood types like A-positive shared by a large population segment.
  • This limitation meant blood evidence could not reliably narrow down suspects.

Purpose of the Study:

  • To highlight the evolution of forensic identification techniques.
  • To emphasize the advantages of DNA profiling over traditional blood typing.
  • To showcase the expanding applications of DNA profiling beyond criminal investigations.

Main Methods:

  • Historical review of forensic identification methods.
  • Comparison of discriminatory power between blood typing and DNA profiling.
  • Overview of advancements in DNA profiling techniques, including PCR and STR analysis.

Main Results:

  • DNA profiling offers significantly higher discriminatory power compared to blood typing.
  • Forensic laboratories have largely replaced blood typing with DNA profiling for casework.
  • The development of DNA databases and techniques like PCR has enhanced DNA profiling's utility.

Conclusions:

  • DNA profiling is the current standard in forensic science due to its precision.
  • The applications of DNA profiling have broadened considerably, extending beyond criminal justice.
  • Future advancements in instrumentation and techniques promise further expansion of DNA profiling's role.