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Related Concept Videos

Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Dosage Regimen: Individualization01:24

Dosage Regimen: Individualization

Individualization in dosing regimens is the customization of medication doses for individual patients. Its necessity arises from the goal of maximizing therapeutic benefits while minimizing risks. This approach is pivotal because human responses to drugs can vary widely; what is effective for one person may be inadequate or excessive for another. Interpatient (intersubject) variability refers to differences in drug responses between individuals, while intrapatient (intrasubject) variability...
Dosage Regimens: Designs and Approaches01:28

Dosage Regimens: Designs and Approaches

Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...
Issues And Trends In Healthcare Delivery System01:29

Issues And Trends In Healthcare Delivery System

The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Dosage Regimen: Fixed Dose01:01

Dosage Regimen: Fixed Dose

Fixed-dose regimens are a common approach to administer drugs to achieve and maintain desired levels of the drug in the body. In this dosing strategy, a specific amount of medication is given at regular intervals, often multiple times a day, to ensure a consistent drug concentration in the bloodstream.
Fixed-dose regimens can be used for various routes of administration, including intravenous (IV) injections and oral medications. For IV administration, a predetermined amount of the drug is...
Health Information Technology and Healthcare Information System01:30

Health Information Technology and Healthcare Information System

Health Information Technology (HIT)
Health Information Technology, commonly called HIT, integrates advanced information systems and technology in healthcare settings. Its primary functions include:

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Related Experiment Video

Updated: May 21, 2026

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

Medication adherence changes following value-based insurance design.

Joel F Farley1, Daryl Wansink, Jennifer H Lindquist

  • 1Division of Pharmaceutical Outcomes and Policy, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599-7360, USA. jffarley@unc.edu

The American Journal of Managed Care
|June 15, 2012
PubMed
Summary
This summary is machine-generated.

Value-based insurance design (VBID) improved medication adherence for cardiometabolic conditions. The greatest improvements were seen in patients who were not adherent before the program.

Related Experiment Videos

Last Updated: May 21, 2026

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

Area of Science:

  • Health Services Research
  • Pharmacoeconomics
  • Public Health

Background:

  • Medication nonadherence is a significant barrier to effective management of chronic cardiometabolic conditions.
  • Value-based insurance design (VBID) programs aim to reduce cost-related barriers to medication access.
  • Previous research on VBID's impact on medication adherence has yielded mixed results.

Purpose of the Study:

  • To evaluate the association between participation in a VBID program and medication adherence.
  • To assess adherence changes in 8 drug classes 2 years post-implementation.
  • To examine if adherence improvements varied based on baseline adherence levels.

Main Methods:

  • A pre-post quasi-experimental study design with a retrospective cohort of 74,748 enrollees.
  • Analysis of medication possession ratio (MPR) from refill records for 8 therapeutic classes.
  • Propensity-matched cohorts and generalized estimating equations were used to estimate adherence.

Main Results:

  • VBID was associated with improved medication adherence, ranging from 1.4% to 3.2% at 1 year, and 2.1% to 5.2% at 2 years.
  • Adherence improvements were most pronounced in patients with low baseline adherence (MPR <.50).
  • The study controlled for potential confounders through propensity matching.

Conclusions:

  • Population-based VBID implementation can enhance medication adherence for cardiometabolic conditions.
  • VBID demonstrates particular benefit for patients previously struggling with adherence.
  • Future VBID guidelines should consider individual patient responses for optimal program design.