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In vitro studies on lymphocyte Fc gamma receptor blocking factors in human renal transplantation

G P Sandilands1, J Highet, D Degiannis

  • 1University Department of Pathology, Western Infirmary, Glasgow, U.K.

Immunology Letters
|November 1, 1990
PubMed

In this study we have confirmed our earlier observation that the presence in pre-transplant serum of a high-molecular-weight lymphocyte Fc gamma receptor blocking factor correlates with improved human renal allograft survival. This factor was found to bind preferentially to B cells and to impair B cell function in vitro.

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