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Related Experiment Video

Updated: May 21, 2026

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
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Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection

Published on: August 15, 2025

Endoscopic craniofacial resection. Indications and technical aspects.

José Luis Llorente1, Fernando López, Vanessa Suárez

  • 1Unidad de Base de Cráneo, Servicio de Otorrinolaringología, Instituto Universitario de Oncología del Principado de Asturias, Hospital Universitario Central de Asturias, Oviedo, España. llorentependas@telefonica.net

Acta Otorrinolaringologica Espanola
|June 15, 2012
PubMed
Summary

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Endoscopic anterior craniofacial resection (CFR) offers a viable alternative for anterior skull base tumors. This minimally invasive approach demonstrated high complete resection rates and favorable survival outcomes in a recent study.

Area of Science:

  • Neurosurgery
  • Otolaryngology
  • Head and Neck Surgery

Background:

  • Anterior craniofacial resection (CFR) is a standard surgical procedure for anterior skull base tumors.
  • Endoscopic techniques are increasingly explored for minimally invasive tumor removal.

Purpose of the Study:

  • To evaluate the efficacy and safety of endoscopic anterior CFR.
  • To present the institutional experience with this technique.

Main Methods:

  • Retrospective analysis of 32 patients treated with endoscopic anterior CFR between 2004 and 2011.
  • Analysis of pathological findings, TNM staging, complication rates, resection completeness, recurrence, and survival data.

Main Results:

  • Adenocarcinoma was the most common diagnosis (60%).

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  • High complete resection rate (91%) with a low complication rate (6%).
  • 5-year overall survival was 70%, and disease-free survival was 85% with 9% recurrence.

    • Conclusions:

    • Endoscopic anterior CFR is a safe and effective alternative to open surgery for anterior skull base malignancies.
    • Proper planning is crucial for successful outcomes with this minimally invasive approach.