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Updated: May 21, 2026

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function
Published on: April 12, 2024
MRI of the lung (3/3)-current applications and future perspectives
Jürgen Biederer1, S Mirsadraee, M Beer
1Department of Diagnostic Radiology, University Hospital Schleswig-Holstein, Campus Kiel, Arnold-Heller-Straße. 3, Haus 23, 24105, Kiel, Germany, juergen.biederer@rad.uni-kiel.de.
Magnetic resonance imaging (MRI) is emerging as a valuable lung imaging tool, offering a radiation-free alternative. It shows promise as a first-choice method for conditions like cystic fibrosis and pulmonary embolism, especially in younger or pregnant patients.
Area of Science:
- Radiology
- Medical Imaging
- Pulmonology
Background:
- Magnetic resonance imaging (MRI) is increasingly recommended for various lung conditions.
- It offers a crucial non-radiation imaging alternative, particularly beneficial for pediatric and pregnant populations.
Purpose of the Study:
- To discuss the advantages and limitations of lung MRI in current clinical practice.
- To highlight its role as a complementary or alternative imaging modality.
Main Methods:
- Utilizes customized chest imaging protocols combining fast breath-hold acquisitions.
- Employs a variety of MRI sequences tailored for lung imaging.
Main Results:
- Lung MRI provides additional functional information on respiratory mechanics and perfusion.
- It demonstrates diagnostic value comparable to other modalities for tumors and pneumonia in children.
- Its clinical utility in interstitial lung disease is under investigation but shows research potential.
Conclusions:
- MRI is evolving as a third major lung imaging modality, integrating morphological and functional data.
- It is considered a primary choice for cystic fibrosis and pulmonary embolism in specific patient groups.
- Future developments include motion-compensated and fast Fourier decomposition MRI for advanced imaging.
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