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Updated: May 21, 2026

Phase-Resolved Functional Lung MRI for Pulmonary Ventilation and Perfusion (V/Q) Assessment
Published on: August 9, 2024
Pulmonary perfusion imaging using MRI: clinical application
Sebastian Ley1, Julia Ley-Zaporozhan
1Division of Cardiothoracic Imaging, Department of Medical Imaging, Toronto General Hospital, University of Toronto and University Health Network, Toronto General Hospital, 585 University Avenue, Toronto, Ontario, M5G 2N2, Canada, ley@gmx.de.
Background:
Lung perfusion is one of the key components of oxygenation. It is hampered in pulmonary arterial diseases and secondary due to parenchymal diseases.
Methods:
Assessment is frequently required during the workup of a patient for either of these disease categories.
Results:
This review provides insight into imaging techniques, qualitative and quantitative evaluation, and focuses on clinical application of MR perfusion.
Conclusion:
The two major techniques, non-contrast-enhanced (arterial spin labeling) and contrast-enhanced perfusion techniques, are discussed.
Insights
This review explores Magnetic Resonance (MR) perfusion imaging for assessing lung perfusion, crucial for oxygenation. It details techniques and clinical applications for pulmonary and parenchymal diseases.
Area of Science:
- Radiology
- Medical Imaging
- Pulmonary Medicine
Background:
- Lung perfusion is vital for oxygenation.
- Pulmonary arterial and parenchymal diseases impair lung perfusion.
- Accurate assessment is critical for patient workup.
Purpose of the Study:
- To provide insight into imaging techniques for lung perfusion assessment.
- To focus on the clinical application of MR perfusion.
- To discuss qualitative and quantitative evaluation methods.
Main Methods:
- Review of current literature on MR perfusion imaging.
- Discussion of non-contrast-enhanced (arterial spin labeling) techniques.
- Exploration of contrast-enhanced perfusion techniques.
Main Results:
- MR perfusion offers valuable insights into lung perfusion.
- Both qualitative and quantitative evaluation methods are discussed.
- Clinical applications in pulmonary and parenchymal diseases are highlighted.
Conclusions:
- MR perfusion imaging is a key tool for evaluating lung perfusion.
- Arterial spin labeling and contrast-enhanced techniques are major methods.
- Understanding these techniques aids in diagnosing and managing lung diseases.
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