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Online Transcranial Magnetic Stimulation Protocol for Measuring Cortical Physiology Associated with Response Inhibition
08:55

Online Transcranial Magnetic Stimulation Protocol for Measuring Cortical Physiology Associated with Response Inhibition

Published on: February 8, 2018

Uncoupling response inhibition.

Hayley J Macdonald1, Cathy M Stinear, Winston D Byblow

  • 1Department of Sport and Exercise Science, The University of Auckland, Auckland, New Zealand.

Journal of Neurophysiology
|June 15, 2012
PubMed
Summary
This summary is machine-generated.

Preventing specific movements delays others, especially when actions are similar. This suggests a unified response inhibition and selective re-initiation process in the motor system.

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Last Updated: May 21, 2026

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Irrelevant Stimuli and Action Control: Analyzing the Influence of Ignored Stimuli via the Distractor-Response Binding Paradigm

Published on: May 14, 2014

Area of Science:

  • Neuroscience
  • Motor Control
  • Cognitive Psychology

Background:

  • Voluntary movement control involves complex inhibitory processes.
  • Selective response inhibition is crucial for adapting behavior in dynamic environments.
  • Previous research suggests response inhibition mechanisms are sensitive to action characteristics.

Purpose of the Study:

  • To investigate how the similarity between prevented and continued actions affects motor response inhibition.
  • To determine if response inhibition is selective or global for prepared movements.
  • To explore the neural mechanisms underlying anticipatory response inhibition.

Main Methods:

  • Fifteen healthy participants completed an anticipatory response inhibition task.
  • The task involved homogeneous (same digit) and heterogeneous (different digits) movement pairings (index finger extension, thumb abduction).
  • Measures included response times, inter-digit asynchrony, and electromyography (EMG) of specific muscles.

Main Results:

  • Selective inhibition trials delayed the execution of the remaining movement compared to simple execution trials.
  • Response delays were sensitive to action similarity, occurring later with homogeneous pairings.
  • Successful inhibition involved suppressing the entire response, followed by selective reinitiation.

Conclusions:

  • Motor output inhibition appears to operate on a unitary response rather than selectively.
  • Selective reinitiation of motor commands is a key component of response inhibition.
  • Homogeneous action pairings require greater inhibitory control and motor system gain.