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Roth spots in pernicious anaemia.
1Department of General Medicine, NHS, James Cook University Hospital, Middlesbrough, UK. mavin_m@yahoo.co.uk
BMJ Case Reports
|June 15, 2012
Summary
Roth spots, white-centred retinal haemorrhages, can indicate pernicious anaemia. Prompt diagnosis and vitamin B12 treatment resolved both anaemia and these eye findings.
Area of Science:
- Ophthalmology
- Hematology
- Internal Medicine
Background:
- Roth spots are distinctive retinal haemorrhages.
- Historically, they were considered pathognomonic for subacute bacterial endocarditis.
- However, various conditions can present with Roth spots.
Observation:
- This case report details a rare association between Roth spots and pernicious anaemia.
- The patient presented with clinical signs suggestive of both conditions.
Findings:
- The diagnosis of pernicious anaemia was confirmed.
- Treatment involved intramuscular vitamin B12 injections.
- Complete resolution of both the anaemia and the Roth spots was observed post-treatment.
Implications:
- This case highlights the importance of considering pernicious anaemia in the differential diagnosis of Roth spots.
- Prompt investigation and management are crucial for favourable outcomes.
- Clinicians should be aware of this rare but treatable association.
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