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Updated: May 21, 2026

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)

Published on: September 14, 2010

Kaposi sarcoma presenting as dermal nodule.

Kiran Alam¹, Veena Maheshwari, Manoranjan Varshney

¹Department of Pathology, JN Medical College, Aligarh, India.

BMJ Case Reports

|June 15, 2012

Summary

Kaposi sarcoma (KS), a rare tumor caused by human herpes virus 8, can manifest as skin lesions. This case highlights a classic subtype presentation in a 60-year-old male with a hand nodule.

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Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)

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Published on: September 14, 2010

An In Vitro Model for Studying Cellular Transformation by Kaposi Sarcoma Herpesvirus

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Published on: August 25, 2017

Area of Science:

Oncology
Virology
Dermatology

Background:

Kaposi sarcoma (KS) is an oncological complication associated with human herpes virus 8 (HHV-8) infection.
KS is a systemic vascular tumor that can affect the skin and internal organs.

Observation:

A 60-year-old male presented with a 4-month history of a nodular lesion on his right hand.
The lesion's characteristics were consistent with the classic subtype of Kaposi sarcoma.

Findings:

The case details the clinical presentation and diagnostic considerations for classic Kaposi sarcoma.
The nodular lesion on the hand served as the primary manifestation of the disease.

Implications:

This case underscores the importance of recognizing diverse KS presentations, even in immunocompetent individuals.
Early diagnosis and management of Kaposi sarcoma are crucial for patient outcomes.
Further research into HHV-8 pathogenesis and KS treatment strategies remains essential.