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Updated: May 21, 2026

Assessment of the Cytotoxic and Immunomodulatory Effects of Substances in Human Precision-cut Lung Slices
Published on: May 9, 2018
[Exposure to leather dusts and organic solvents--results of the PPTP-shoe study]
Danilo Cottica1, Elena Grignani, Angelo Berri
1Centro Ricerche Ambientali--Fondazione Salvatore Maugeri--I.R.C.C.S.--Padova. danilo.cottica@fsm.it
Abstract:
In the shoe industry leather dusts and organic solvents present in glues can be identified as a significant chemical risks. To assess the level of occupational exposure a sector study was conducted on small to medium size companies: in 9 were measured the respirable and inhalable dust concentrations and in 13 the solvents. The measurements were performed using personal samplers. The results confirmed the assumed Similar Exposure Group (SEG). The average concentrations of dust were well below the TLV-TWA, the Mixture Index for the solvents is exceeded in 9 out of 67 cases, the "critical" solvent has proven to be cyclohexane.
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