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Related Concept Videos

Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Diversity of Protists II01:27

Diversity of Protists II

Alveolates are a group of organisms recognized by the presence of alveoli, which are cytoplasmic sacs located beneath the cell membrane. While their function remains uncertain, alveoli may help regulate water balance by controlling how much water enters and leaves the cell. In dinoflagellates, these structures may serve as armor plates. There are three major types of alveolates: ciliates, which move using cilia; dinoflagellates, which use flagella for movement; and apicomplexans, which are...
Cholecystitis01:20

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
Diverticular Disease of the Colon01:27

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...

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Related Experiment Video

Updated: May 21, 2026

A Simple Protocol for Platelet-mediated Clumping of Plasmodium falciparum-infected Erythrocytes in a Resource Poor Setting
07:27

A Simple Protocol for Platelet-mediated Clumping of Plasmodium falciparum-infected Erythrocytes in a Resource Poor Setting

Published on: May 16, 2013

Falciparum malaria masquerading as appendicitis.

Anand Kumar Bhardwaj1, P D Sharma, Akshay Sharma

  • 1Department of Paediatrics, MM Institute of Medical Sciences and Research, Ambala, India. col.akbhardwaj@gmail.com

BMJ Case Reports
|June 16, 2012
PubMed
Summary
This summary is machine-generated.

A rare case of falciparum malaria in a child mimicked acute appendicitis in India. The condition, unresponsive to artemether, highlighted potential drug resistance and the need for high clinical suspicion for malaria diagnosis.

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Area of Science:

  • Tropical Medicine
  • Infectious Diseases
  • Clinical Case Reports

Background:

  • Falciparum malaria is a severe, multi-organ disease with high incidence in India.
  • Varied clinical presentations can complicate malaria diagnosis, necessitating physician vigilance.
  • Emerging drug resistance in malaria poses a significant public health challenge.

Observation:

  • An unusual pediatric case presented with symptoms mimicking acute appendicitis.
  • The patient underwent surgery, revealing an inflamed appendix.
  • Postoperative complications included symptoms suggestive of acute renal failure.

Findings:

  • The case demonstrated falciparum malaria presenting atypically as acute appendicitis.
  • Lack of response to artemether therapy indicated potential artemisinin resistance.
  • Delayed diagnosis and treatment contributed to a complicated clinical course.

Implications:

  • This case underscores the importance of considering malaria in differential diagnoses, even with seemingly surgical presentations.
  • It highlights the growing threat of drug-resistant malaria strains in endemic regions.
  • Prompt diagnosis and appropriate antimalarial therapy are crucial for managing severe malaria and preventing complications.