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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Related Experiment Video

Updated: May 21, 2026

A Melanoma Patient-Derived Xenograft Model
07:07

A Melanoma Patient-Derived Xenograft Model

Published on: May 20, 2019

Subungual malignant melanoma--re-learning the lesson.

Kavit Amin1, Katy Edmonds, Andrew Fleming

  • 1St George's Medical School, London, UK. kavamin@yahoo.co.uk

BMJ Case Reports
|June 16, 2012
PubMed
Summary

Subungual malignant melanoma can mimic traumatic hand injuries. Early diagnosis of nail bed lesions is crucial, especially in emergency settings, to ensure timely cancer treatment.

Area of Science:

  • Dermatology
  • Oncology
  • Hand Surgery

Background:

  • Traumatic hand injuries are common presentations in emergency care.
  • Pigmented lesions under the nail bed can be challenging to differentiate from trauma.

Observation:

  • Two patients presented with suspected traumatic hand injuries.
  • Clinical examination revealed pigmented lesions beneath the nail bed in both cases.

Findings:

  • Biopsies confirmed subungual malignant melanoma in both patients.
  • The initial presentation mimicked traumatic injury, delaying diagnosis.

Implications:

  • Highlights the importance of thorough dermatological assessment in hand injuries.
  • Emphasizes the need for increased awareness of subungual melanoma in emergency medicine.

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  • Suggests biopsy for persistent or suspicious pigmented nail lesions.