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Related Experiment Videos

Crack-induced enteric ischemia.

D C Hon1, L J Salloum, H W Hardy

  • 1Department of Surgery, St. Francis Medical Center, Trenton, NJ 08629.

New Jersey Medicine : the Journal of the Medical Society of New Jersey
|December 1, 1990
PubMed
Summary
This summary is machine-generated.

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Cocaine use can rarely cause intestinal ischemia. This case report details the first instance of mesenteric infarction linked to crack abuse, previously associated only with gastroduodenal ulcer perforation.

Area of Science:

  • Gastroenterology
  • Vascular Surgery
  • Toxicology

Background:

  • Cocaine use is a known risk factor for various gastrointestinal complications.
  • Previous reports have linked crack abuse to gastroduodenal ulcer perforation.
  • Mesenteric infarction is a rare but severe vascular emergency.

Observation:

  • This case report describes a patient who developed mesenteric infarction following crack cocaine abuse.
  • The patient presented with symptoms consistent with acute intestinal ischemia.
  • Diagnostic imaging confirmed extensive mesenteric artery thrombosis.

Findings:

  • This is the first documented case associating crack abuse directly with mesenteric infarction.
  • The findings suggest a potential mechanism linking stimulant-induced vasoconstriction to ischemic events in the mesenteric vasculature.

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  • Histopathological examination may reveal specific vascular changes related to crack cocaine toxicity.

    • Implications:

    • This case expands the spectrum of gastrointestinal complications associated with crack cocaine use.
    • It highlights the importance of considering illicit drug use in the differential diagnosis of acute mesenteric ischemia.
    • Further research is needed to elucidate the precise pathophysiology and prevalence of this association.