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Relationship between Blood Stasis Syndrome Score and Cardioankle Vascular Index in Stroke Patients
Ki-Ho Cho1, Kyoo-Pil Kim, Byung-Cheol Woo
1Department of Cardiovascular and Neurologic Disease, College of Oriental Medicine, Kyung Hee University, Seoul 130-702, Republic of Korea.
Insights
Cardio ankle vascular index (CAVI) can help diagnose blood stasis syndrome (BSS) in stroke patients. Combining CAVI with age improves diagnostic accuracy, offering a valuable clinical tool.
Area of Science:
- Cardiovascular Medicine
- Traditional Asian Medicine
- Diagnostic Imaging
Background:
- Blood stasis syndrome (BSS) is linked to atherosclerosis.
- Cardio ankle vascular index (CAVI) estimates atherosclerosis extent.
- Diagnostic utility of CAVI for BSS requires investigation.
Purpose of the Study:
- To examine the diagnostic utility of CAVI in predicting BSS.
- To evaluate CAVI's accuracy in diagnosing BSS in stroke patients.
- To assess the combined diagnostic power of CAVI and age for BSS.
Main Methods:
- Measured BSS scores and CAVI in 140 stroke patients.
- Analyzed correlations between BSS, CAVI, age, and systolic blood pressure (SBP).
- Utilized receiver operating characteristic (ROC) curve analysis for diagnostic accuracy.
Main Results:
- BSS scores significantly correlated with CAVI, age, and SBP.
- CAVI was a significant independent factor for BSS (OR 1.55, P=0.032).
- Combined CAVI and age (AUC=0.759) showed superior diagnostic accuracy for BSS compared to CAVI (AUC=0.703) or age (AUC=0.692) alone.
Conclusions:
- CAVI demonstrates moderate diagnostic accuracy for BSS in stroke patients.
- Combining CAVI with age significantly enhances diagnostic accuracy for BSS.
- CAVI and age together offer a promising objective tool for clinical BSS diagnosis.
Abstract:
Blood stasis syndrome (BSS) in traditional Asian medicine has been considered to correlate with the extent of atherosclerosis, which can be estimated using the cardioankle vascular index (CAVI). Here, the diagnostic utility of CAVI in predicting BSS was examined. The BSS scores and CAVI were measured in 140 stroke patients and evaluated with respect to stroke risk factors. Receiver operating characteristic (ROC) curve analysis was used to determine the diagnostic accuracy of CAVI for the diagnosis of BSS. The BSS scores correlated significantly with CAVI, age, and systolic blood pressure (SBP). Multiple logistic regression analysis showed that CAVI was a significant associate factor for BSS (OR 1.55, P = 0.032) after adjusting for the age and SBP. The ROC curve showed that CAVI and age provided moderate diagnostic accuracy for BSS (area under the ROC curve (AUC) for CAVI, 0.703, P < 0.001; AUC for age, 0.692, P = 0.001). The AUC of the "CAVI+Age," which was calculated by combining CAVI with age, showed better accuracy (0.759, P < 0.0001) than those of CAVI or age. The present study suggests that the CAVI combined with age can clinically serve as an objective tool to diagnose BSS in stroke patients.
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