Related Experiment Video
Updated: May 21, 2026

Applying a Three-dimensional Uniaxial Mechanical Stimulation Bioreactor System to Induce Tenogenic Differentiation of Tendon-Derived Stem Cells
Published on: August 1, 2020
[Expression of mechano-growth factor and its roles in tissue repairs and regeneration]
Bingyu Zhang1, Guanbin Song, Qing Luo
1College of Bioengineering, Chongqing University, Chongqing 400044, PR China.
Objective:
To review the expression of mechano-growth factor (MGF) and its roles in tissue repairs and regeneration.
Methods:
The literature about the expression of MGF and its roles in tissue repairs and regeneration in recent years was reviewed.
Results:
MGF is sensitive to mechanical stimulation and can be expressed in various tissues/cells. MGF is responsible for satellite cell activation, myoblast proliferation, and plays important roles in the treatment of muscle coloboma, prevention of myocardial injury, and neuroprotection.
Conclusion:
The important role of MGF in tissue repairs and regeneration has been identified, however, the detailed mechanisms remain unclear up to now and still need a further study.
Related Concept Videos
Healing I: Introduction
Role of Matrix Metalloproteases in Degradation of ECM
A...
Mitogens and the Cell Cycle
Overview of Regeneration and Repair
Regeneration
All animals have varying degrees of...
Cell-matrix's Response to Mechanical Forces
Anchoring junctions mechanically attach a cell to the...
The Extracellular Matrix
