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Updated: May 21, 2026

Intradermal Inoculation of Mycobacterium avium in the Mouse Ear
Published on: July 3, 2025
[Mycobacterium immunogenum isolated from a metal worker in Japan]
Harutaka Omura1, Akira Kajiki, Satoshi Ikegame
1Department of Respiratory Medicine, National Hospital Organization Omuta National Hospital, 1044-1, Tachibana, Ohmuta-shi, Fukuoka 837-0911, Japan. oomura-h@oomuta-h.com
Abstract:
In the United States and European countries, Mycobacterium immunogenum has been identified in metalworking fluids and is reported to be a causative agent of metalworking fluid-associated hypersensitivity pneumonitis. However, in Japan, there has been no reports of M. immunogenum isolated from metalworking fluids. This is the first report of isolation of the microorganism from the sputum of a metal-grinding machine worker in Japan. We should consider the possibility of M. immunogenum infection in case of non-tuberculosis mycobacteriosis and hypersensitivity pneumonitis in metalworkers.

