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Updated: May 21, 2026

Fibroblast Derived Human Engineered Connective Tissue for Screening Applications
Published on: August 20, 2021
From clinical experience to a model for the human fascial system
Julie Ann Day1, Lorenzo Copetti2, Giorgio Rucli3
1Centro Socio Sanitario dei Colli, Physiotherapy, Azienda Ulss 16, Via dei Colli 4, Padova, Italy.
Abstract:
Studies of fascial anatomy, histology, and physiology are changing comprehension of the role of fascia in many body functions. In the light of these studies, evidence-based models of the human fascial system that provide immediate clinical applications for manual therapists working with movement dysfunctions and pain are necessarily evolving. This paper presents an overview of one proposed biomechanical model and discusses some of its underlying hypotheses. Developed initially from extensive review of anatomical texts and clinical experience, subsequent anatomical dissections, histological, biomechanical, and some clinical studies have investigated this model. These studies are discussed, also in reference to other contemporary musculoskeletal research. This model for the human fascial system could represent new perspectives for clinicians and researchers regarding the functional integration of fascia within the musculoskeletal system.
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