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Updated: May 21, 2026

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis
06:45

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis

Published on: February 10, 2023

Characterization of central venous catheter-associated deep venous thrombosis in infants

Brian W Gray1, Raquel Gonzalez, Kavita S Warrier

  • 1Section of Pediatric Surgery, C.S. Mott Children's Hospital, University of Michigan Health System, Ann Arbor, MI 48109, USA.

Journal of Pediatric Surgery
|June 19, 2012
PubMed

Insights

Central venous catheter (CVC) use in infants is linked to deep venous thrombosis (DVT). Avoiding percutaneous femoral and multilumen CVCs, screening lines, and early removal can reduce DVT risk.

Area of Science:

  • Pediatric Thrombosis
  • Vascular Access Devices
  • Neonatal Intensive Care

Background:

  • Deep venous thrombosis (DVT) is a significant complication in infants requiring central venous catheters (CVCs).
  • Identifying risk factors and effective prevention strategies for CVC-associated DVT in this vulnerable population is crucial.

Purpose of the Study:

  • To identify risk factors associated with CVC-related DVT in infants.
  • To explore risk-reduction strategies for preventing DVT in infants with CVCs.

Main Methods:

  • Retrospective review of infants under 1 year old with CVCs from 2005-2009.
  • Comparison of patients with ultrasonically diagnosed DVT versus those without radiographic evidence.

Main Results:

  • Femoral CVCs showed higher DVT rates (27%) compared to jugular (11%) and subclavian (9%) sites.
  • Percutaneous femoral lines (83% DVT rate) and multilumen CVCs (54% DVT rate) were associated with significantly higher DVT incidence.
  • Patients with DVT had longer hospital stays and increased ICU admission rates.

Conclusions:

  • Strategies to reduce DVT in infants with CVCs include avoiding percutaneous femoral and multilumen catheters.
  • Screening of percutaneous lines and prompt catheter removal are recommended for DVT prevention.
Abstract

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