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Related Concept Videos

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease IV: Clinical Manifestations01:20

Inflammatory Bowel Disease IV: Clinical Manifestations

Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The disease course is marked...

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Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
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Published on: August 26, 2014

Small bowel endoscopy in inflammatory bowel disease.

Edward J Despott1, Chris Fraser

  • 1Wolfson Unit for Endoscopy, St Mark's Hospital and Academic Institute, Imperial College London (Northwick Park Campus), Watford Road, Harrow, London HA1 3UJ, UK. edespott@doctors.org.uk

Best Practice & Research. Clinical Gastroenterology
|June 19, 2012
PubMed
Summary

Recent advances in small bowel (SB) endoscopy, including SB capsule endoscopy (SBCE) and device-assisted enteroscopy (DAE), offer new diagnostic and therapeutic options for inflammatory bowel disease (IBD). Their precise role alongside other imaging technologies is still being defined.

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Investigating Intestinal Inflammation in DSS-induced Model of IBD
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Investigating Intestinal Inflammation in DSS-induced Model of IBD
08:43

Investigating Intestinal Inflammation in DSS-induced Model of IBD

Published on: February 1, 2012

Area of Science:

  • Gastroenterology
  • Endoscopy
  • Inflammatory Bowel Disease (IBD)

Background:

  • Small bowel endoscopy has undergone significant technological advancements in the past decade.
  • Traditional methods like push enteroscopy and intra-operative enteroscopy have been complemented by less invasive techniques.
  • Small bowel capsule endoscopy (SBCE) and device-assisted enteroscopy (DAE) now allow for complete visualization of the small bowel without surgery.

Purpose of the Study:

  • To review the current evidence on SBCE and DAE in the diagnosis and management of IBD.
  • To clarify the role of these endoscopic technologies within the broader clinical paradigm for IBD.
  • To highlight current international recommendations regarding their use.

Main Methods:

  • Review of existing literature and evidence on small bowel endoscopy technologies.
  • Analysis of the impact of SBCE and DAE on IBD diagnosis and management.
  • Synthesis of international recommendations for the application of these technologies.

Main Results:

  • SBCE and DAE have revolutionized small bowel visualization, enabling non-surgical endoscopic examination of the entire small bowel.
  • DAE offers the advantage of tissue sampling and endotherapy application.
  • While their potential in IBD is recognized, their specific place relative to other diagnostic tools requires further definition.

Conclusions:

  • SBCE and DAE represent significant advancements in visualizing the small bowel for IBD assessment.
  • Further research and clinical consensus are needed to establish the optimal integration of these technologies into IBD management.
  • International guidelines are emerging to help navigate the use of these innovative endoscopic tools.