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Semi-synthesis and bio-evaluation of polybrominated diphenyl ethers from the sponge Dysidea herbacea
T Srikanth Reddy1, N Suryakiran, M Narasimhulu
1Natural Products Chemistry Division, Natural Products Laboratory, Indian Institute of Chemical Technology, Hyderabad 500 007, India.
Bioorganic & Medicinal Chemistry Letters
|June 19, 2012
Abstract:
The sponge Dysidea herbacea was collected from the Mandapam Coast, Tamilnadu, India. Isolated gram quantities of hydroxylated polybrominated diphenyl ether (HO-PBDE) and semi-synthesized a series of new PBDEs derivatives and tested them for antibacterial and cytotoxic activities.
