Oxidative stress and metal carcinogenesis

Jeong-Chae Lee1, Young-Ok Son, Poyil Pratheeshkumar

  • 1Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, KY 40536, USA.

Summary

Metals exposure increases cancer risk by generating reactive oxygen species (ROS). This review explores metal-induced ROS, their link to cancer, and key signaling proteins involved in metal-mediated carcinogenesis.

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