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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...

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Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking
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Impaired saccadic eye movement in primary open-angle glaucoma.

Cédric Lamirel1, Dan Milea, Isabelle Cochereau

  • 1*Ophthalmology Department, Fondation Ophtalmologique Adolphe de Rothschild †Ophthalmology Department, Hôpital Bichat-Claude Bernard ‡CRICM, Cogimage, Université Pierre et Marie Curie, UMR 7225, CNRS, INSERM, Paris §Ophthalmology Department, Angers University Hospital, Angers, France ∥Glostrup University Hospital, Copenhagen, Denmark.

Journal of Glaucoma
|June 19, 2012
PubMed
Summary

Primary open-angle glaucoma (POAG) disrupts saccadic eye movements, especially when tracking moving targets. This impacts eye movement accuracy and latency in patients with POAG.

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Area of Science:

  • Ophthalmology
  • Neuroscience
  • Visual Science

Background:

  • Primary open-angle glaucoma (POAG) is a leading cause of irreversible blindness.
  • Previous research noted altered eye movement behavior in POAG patients during visual scene exploration.

Purpose of the Study:

  • To investigate the disruption of saccadic eye movements in patients with POAG.
  • To determine if visual field scotoma influences saccadic eye movement abnormalities in POAG.

Main Methods:

  • Recorded saccadic eye movements in 8 POAG patients (4 with scotoma, 4 without) and 4 healthy controls.
  • Monitored eye movements during static and kinetic target viewing.
  • Analyzed saccade gain, latency, and velocity-peak latency.

Main Results:

  • POAG patients with visual field defects showed delayed and less accurate saccades towards static targets.
  • Both POAG patient groups (with and without visual field defects) exhibited impaired saccade latency and accuracy when tracking kinetic targets.

Conclusions:

  • Primary open-angle glaucoma significantly alters saccade programming and execution.
  • The disruption is particularly evident when POAG patients attempt to track moving targets.