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Application of Acupotomy in a Knee Osteoarthritis Model in Rabbit
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Published on: October 20, 2023

Sex differences in quadriceps strength in OA.

M J Berger1, C A McKenzie, D G Chess

  • 1Schulich School of Medicine & Dentistry, The University of Western Ontario, London, Canada. mberger2010@meds.uwo.ca

International Journal of Sports Medicine
|June 19, 2012
PubMed
Summary

Sex differences in knee osteoarthritis (OA) quadriceps strength persist even after accounting for muscle size. However, these differences diminish significantly, suggesting other factors influence strength beyond muscle volume.

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Area of Science:

  • Orthopedics
  • Sports Medicine
  • Human Physiology

Background:

  • Knee osteoarthritis (OA) is a prevalent condition affecting joint function.
  • Sex differences in muscle strength are well-documented but less understood in OA populations.
  • Muscle volume is a key determinant of muscle force production.

Purpose of the Study:

  • To investigate sex differences in quadriceps torque and power, normalized for muscle volume, in individuals with knee OA.
  • To identify factors contributing to any observed sex differences in muscle function.

Main Methods:

  • Assessed isometric torque, isotonic power, and maximal unloaded velocity in men and women with knee OA.
  • Normalized torque and power to quadriceps muscle volume.
  • Utilized the interpolated twitch technique for voluntary activation (VA) assessment.
  • Measured evoked twitch and torque-frequency characteristics to evaluate muscle fiber properties.

Main Results:

  • Women exhibited significantly lower torque and power across all tested loads compared to men.
  • Normalizing for muscle volume reduced sex differences in power by 50%, though significant differences remained at lower contraction intensities (10-40% MVC).
  • No significant sex differences were found in voluntary activation, torque-frequency properties, or twitch contractile characteristics.

Conclusions:

  • Minor sex differences in quadriceps torque and power persist in knee OA patients when muscle volume is considered.
  • Voluntary activation and intrinsic muscle contractile properties do not appear to explain these remaining sex differences.
  • Other unmeasured factors likely contribute to the observed sex disparities in muscle function in this population.