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[Rotavirus gastro-enteritis in infants (author's transl)]
La Semaine Des Hopitaux : Organe Fonde Par L'Association D'Enseignement Medical Des Hopitaux De Paris
|May 18, 1979
Summary
Rotavirus gastroenteritis in infants under 18 months showed significant complement antibody deviation, particularly from November to March. This highlights the need for targeted interventions during peak seasons for young children.
Area of Science:
- Pediatric Infectious Diseases
- Immunology
- Virology
Context:
- Rotavirus gastroenteritis is a common cause of hospitalization in infants.
- Understanding the immune response, specifically complement antibodies, is crucial for managing severe cases.
- This study investigated immune deviations in hospitalized infants with rotavirus infections.
Purpose:
- To analyze complement antibody deviations in infants hospitalized with rotavirus gastroenteritis.
- To identify age-specific patterns and seasonal trends in rotavirus infections.
- To assess the prevalence of rotavirus as a cause of infant gastroenteritis.
Summary:
- A study of 630 infants (0-4 years) with rotavirus gastroenteritis revealed seroconversion in 30 of 256 infants with paired samples.
- Rotavirus infections with seroconversion predominantly occurred in infants under 18 months, primarily between November and March.
- Rotavirus accounted for one-third of infant gastroenteritis cases, with serological positive rates varying by age group.
Impact:
- Provides insights into the immunological response to rotavirus in young children.
- Informs seasonal and age-specific public health strategies for rotavirus prevention and management.
- Contributes to the understanding of rotavirus epidemiology in hospitalized infant populations.