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Targeting the PI3K pathway for cancer therapy

Navid Sadeghi1, David E Gerber

  • 1Division of Hematology & Oncology, Harold C Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Future Medicinal Chemistry
|June 20, 2012
PubMed
Summary

The phosphoinositide 3-kinase (PI3K) pathway is crucial for cell growth and survival. Understanding its role in cancer is key to developing targeted therapies and overcoming drug resistance.

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